Book Review – Madness and Memory

On the eve of AS exams, I have just finished reading ‘Madness and Memory’ by Stanley B. Prisoner, M.D. It is a book I found when researching for my EPQ and bought back in February, however because of its scientific content, it has taken me a while to get my head around and work through.

Despite this however, I have found it an incredibly interesting book, which appealed to both my love of science and medicine. It is written almost like a diary, a documentation of the events which led to the discovery of prions but explained for those without a science degree (definitely aiding my understanding a huge amount!) making it much more of an easy read.

To me this book highlighted the sheer amount of dedication which goes into research, not something I aspire to do but definitely something I respect. It reflects the skepticisms of new ideas and the rivalries between scientists in bucketloads – a perfect balance of drama and science. The transformation of an unconventional hypothesis – that of protein only (prion) diseases – into what I think is one of the greatest discoveries since the DNA double helix.

I would recommend this book to any budding medical professional or scientist not only because of the way it is written but largely down to its content. Prions are incredibly interesting diseases, and further discoveries could help unravel the unknown about brain diseases – mad cow, Alzheimers, Parkinson’s and Lou Gehrig’s. The debate about the origins of such diseases is what I intend to focus my EPQ on, are they due to cannibalism, food supplements or BSE infected beef? This book has certainly succeeded in piquing my interest in the topic further, and I can’t wait to pick my research up again in a months time, after my exams.

The amazon link to ‘Madness and Memory’ is: https://www.amazon.co.uk/d/Books/Madness-Memory-Discovery-Prions-Biological-Principle-Disease/0300216904/ref=sr_1_1?ie=UTF8&qid=1494614063&sr=8-1&keywords=madness+and+memory

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