What is it?

Schizophrenia is a mental health disorder which sees an individual unable to distinguish their thoughts from their reality. Although there is no notable cause for this disorder, scientists have come to a conclusion it is influenced and stimulated by genetic and environmental factors.

How is it caused?

Genetics play a role, whereby if a relative has the a fault in chromosome 6, the chance of their kin developing a similar trait increases as well. According to further research, genes makes up for 80% of the cause. Environmental factors such as drug abuse can also play a role in increasing the risk of developing schizophrenia, since drugs alter the balance of serotonin and dopamine levels, which also influences schizophrenia developing.

Breakthroughs in research

The C4 gene within chromosome 6 was researched to a great extent within early 2016. Using humans and mice as experiment, it had appeared that scientists had found out that one of the possible causes was because of the C4 gene, via synaptic pruning, was involved in destroying connections between neurons. Synaptic pruning is a process that eliminates these connections to enable more quicker and efficient electrical and chemical signalling. More promising information provided showed that symptoms of Schizophrenia occurred during adolescence, the same time where synaptic pruning is at its peak.


The state of schizophrenia is usually improved by a combination of both therapy and medicine. Therapy can include community mental health teams provided by the NHS. Another service the NHS provides is CPA, which is the care programme approach, whereby you are assessed to enable a care plan to be provided, further appointed a key worker, this could be a social worker for example, and then the treatment is reviewed. Arts therapy is an example of expressing emotion, non-verbally, this s shown to improve the negative symptoms, such as shaking and trembling.

Aman Kumar


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